Vilsmeier-Haack Transformations under Non Classical Conditions

Anisoles and Pyridines undergo acetylation and formylation under non-classical Vilsmeier-Haack conditions. The reactants are grinded vigorously in a mortar for about 25 to 30 min at room temperature with a pestle. The introduction of formyl and acetyl groups under solvent free conditions is a unique, fast and efficient method which has not been reported in literature so far.