Inhibitive Effect on the Rate of Hydrolysis of Tetracaine by the Surfactant-Coated Magnetic Nanoparticles (Fe3O4)

The influence of the magnetic nanoparticles Fe₃O₄ and surfactant coated nanoparticles on the rate of alkaline hydrolysis of tetracaine were investigated spectrophotometrically. The Fe₃O₄ nanoparticles were synthesized by co-precipitation method. These synthesized nanoparticles were characterized by physical techniques. The XRD patterns showed the crystalline nature and the presence of two bands at 635 cm -1 and 585 cm -1 were assigned to the Fe-O bond vibrations in Fe₃O₄. The SEM and TEM studies confirmed the spherical structure of nanoparticles. The VSM studies show the magnetic nature. The reaction rate increased linearly with increase in [NaOH]. The rate constant values decreased with the increase in the SDS coated Fe₃O₄ nanoparticles from 4.0 × 10^-4 s^-1 to 1.1 × 10^-4 s^-1 in the presence of PEG 1500. Similarly, the increase in the amount of CTABr coated