Effects Of Infrared And Ultraviolet Radiation On The Viability Of Cells Immobilized In Porous TiNi-based Alloy Scaffold

Cell responses to electromagnetic radiation are due to many factors including the cellular microenvironment. The aim of the present study was to explore the effects of ultraviolet (UV) and infrared (IR) irradiation of low intensity on cultured cells derived from different biological tissues (spleen, bone marrow, and Ehrlich's adenocarcinoma), which were immobilized in a porous TiNi-based alloy scaffold. Accordingly, the following objectives were set: i) to evaluate the impact of low-intensity radiation on cell suspensions, and ii) to carry out a comparative analysis of the viability of cells immobilized in porous TiNi-based alloy and IR- and UV-irradiated. The data show that the extracellular environment of bone marrow, tumor and spleen cell populations affects their viability and proliferative potency in porous TiNi-based scaffolds. IR- and UV irradiation of cell cultures immobilized in the scaffold affects the cell viability in populations of bone marrow, tumor, and spleen cells.